ANTI MULLERIAN HORMONE- AMH
Pre-test preparation or requirements
• Sample can be drawn at any time. No fasting or special preparation required.
• Sample should taken in plain vial.
0- 2 year 0.9-4.7 ng/ml
3-12 year 0.9-8.8 ng/ml
13-45 year 0.9-9.5 ng/ml
Significance of test
Assay results should be interpreted only in the context with other laboratory findings and the total clinical status of the patient. AMH reference range range given as per test method, and analyser used for testing.
AMH is used to:
-Assess Ovarian Reserve - correlates with the number of antral follicles in the ovaries.
-Evaluate fertility potential and ovarian response in IVF- Women with low AMH levels are more likely to be poor ovarian responders.
-Assess the condition of Polycystic Ovary and premature ovarian failure.
-Evaluate testicular function in infants and children.
-Diagnose and monitor patients with AMH secreting ovarian granulosa cell tumours.
AMH levels increased in:
Polycystic ovarian syndrome. AMH concentrations may be 2 to 5 fold higher than age appropriate reference range values.
AMH levels decreased in:
-Anorchia , Abnormal or absence of testis in males, Pseudohermaphroditism and Post Menopause
AMH measurement alone is seldom sufficient for diagnosis and results should be interpreted in the light of clinical findings and other relevant test results such as Ovarian ultrasonography (in fertility applications); abdominal or testicular ultrasound (intersex or testicular function applications); measurement of sex steroids (estradiol, Progesterone, Testosterone), FSH, Inhibin B (for fertility), and Inhibin A and B (for tumour work up).
Interpretation of AMH levels for women under 35 years of age-
High(Often PCOS) >9.5
Low normal range 0.9-1.5
Very Low <0.5