Pre-test preparation or requirements
• Sample can be drawn at any time. No fasting or special preparation required.
• Sample should taken in plain vial.
Male: 4620 -11500 U/l
Female: 3930 -10800 U/l
Significance of test
Cholinesterase also known as acetyl-cholinesterase and is found mainly in the nerve endings and the grey matter of brain. It hydrolyses acetylcholine, released at the nerve endings to mediate transmission of impulses. A similar enzyme acyl choline acylhydrolase also known as pseudocholinesterase is present in the serum, brain, heart, liver and pancreas but its biological role is unknown. Cholinesterase levels in serum are useful as a test of liver function and as an indicator of possible insecticide poisoning. Among the organic phosphorous compounds that inhibit cholinesterase activity are mainly insectisides such as Parathion, Sarin and Tetraethylpyrophosphate. During poisoning the level of enzymes decreases as its activity is inhibited.