Pre-test preparation or requirements
• Sample can be drawn at any time. No fasting or special preparation required.
• Sample should taken in Citrated vial. Sample should be immediately centrifuged and transfer plasma to aliquot.
Less than 500 mcg/ml FEU
Significance of test
FDPS (fibrin and fibrinogen degradation products) are generic names for several degradation products formed as the result of plasma mediated proteolytic degradation of fibrin and fibrinogen. FDP assay become important test to diagnose or monitor fibrinolytic disorder, especially disseminated intravascular coagulation (DIC). But FDP assay also detects the degradation products of fibrinogenolysis. D- Dimer assay is more specific for fibrinolysis because it can only be produced as the result of plasma mediated proteolytic degradation of fibrin.
The normal range of D-Dimer is less than 0.5 microgram/ml (FEU). D-dimer limits increase in pregnancy and also rises with age. Rheumatoid factor level >50 IU/ml may lead to overestimation of D-Dimer. Highly icteric and hemolysed sample may interfere the reaction.
Results obtained for patient samples are to correlated with clinical findings of patient for interpretation and diagnosis.