DENGUE RAPID TEST
Pre-test preparation or requirements
• Sample can be drawn at any time. No fasting or special preparation required.
• Sample should taken in plain vial.
Significance of test
The mosquito-borne dengue viruses (serotype 1-4) cause dengue fever, a severe flu-like illness. Primary infection with dengue virus results in a self-limiting disease characterized by mild to high grade fever lasting 3 to 7 days, severe headache with pain behind the eyes muscle and joint pain, rash and vomiting. Secondary infection is more serious and can result in DHF and DSS. The major clinical symptoms can include high fever, hemorrhagic events, and circulatory failure, and the fatality rate can be as high as 40%. Primary dengue virus infection is characterized by elevations in specific IgM antibody levels 3 to 5 days after the onset of symptoms; this generally persists for 30 to 60 days. IgG levels also become elevated after 10 to 14 days and remain detectable for life. During secondary infection, IgM levels generally rise more slowly and reach lower levels than in primary infection, while IgG levels rise rapidly from 1 to 2 days after the onset of symptoms.
Rapid card tests are used for screening purpose only and not for diagnosis, the results should be confirmed by ELISA