FOLLICLE STIMULATING HORMONE- FSH
Pre-test preparation or requirements
• Sample can be drawn at any time. But preferred on 2nd day of menstruation. No fasting or special preparation required.
• Sample should taken in plain vial.
Male: 0.9-7.0 mIU/ml
-Follicular Phase 2.0-7.1 mIU/ml
-Ovulation Phase 2.7-12.3 mIU/ml
-Luteal Phase 1.0-4.4 mIU/ml
-Post menopause 14.4-75.5 mIU/ml
Significance of test
The determination of FSH together with LH is generally utilized for diagnosis for diagnosis of the following: abnormal menstrual cycle, amenorrhea, polycystic ovaries (PCO), ovulation disorder, gonadotropin levels in men occur in azoospermia. The ratio of hLH/hFSH is often used for the diagnosis of polycystic ovarian syndrome. FSH deficiency together with low concentration of LH and sex steroids may indicate panhypopituitarism. Because of the negative feedback mechanisms regulation gonadotropin release, elevated concentration of LH and FSH are indicative of gonadal failure when accompanied by low concentration of the gonadal steroids, such as menopause, polycystic ovaries and Turner syndrome. The use of oral contraceptives usually results in reduction of gonadotropin levels due to negative feedback by these steroids. In males, these observations suggest primary testicular failure Klinefelter's syndrome or as a consequence of Sertoli cell failure.