LH/ FSH RATIO
Pre-test preparation or requirements
• Sample can be drawn at any time. But preferred on 2nd day of menstruation. No fasting or special preparation required.
• Sample should taken in plain vial.
Significance of test
The ratio of LH (Luteinizing hormone) to FSH (Follicle-stimulating hormone), when measured in international units, is elevated in women with PCOS. Common cut-offs to designate abnormally high LH/FSH ratios are 2:1or 3:1 as tested on Day 3 of the menstrual cycle. The pattern is not very sensitive; a ratio of 2:1 or higher was present in less than 50% of women with PCOS in one study. There are often low levels of sex hormone-binding globulin in particular among obese or overweight women. Anti-Mullerian hormone (AMH) is increased in PCOS, and may become part of its diagnostic criteria.