LUTEINISING HORMONE- LH
Pre-test preparation or requirements
• Sample can be drawn at any time. But preferred on 2nd day of menstruation. No fasting or special preparation required.
• Sample should taken in plain vial.
Male: 1.4-7.7 mIU/ml
-Follicular Phase 1.9- 11.6 mIU/ml
-Ovulation Phase 12.9-105.2 mIU/ml
-Luteal Phase 0.8-10.5 mIU/ml
-Post menopause 6.6-66.4 mIU/ml
Significance of test
LH and FSH regulate and stimulate the growth and function of the gonads (ovaries and testes) synergistically. LH regulate the menstrual cycle in females with FSH synergistically, causing the release of ovum and the formation of corpus luteum, which secretes progesterone and estradiol. The biosynthesis of LH was controlled by hormone (GnRH). Meanwhile, the ovarian steroids exert either a positive or negative feedback on the release of LH. The determination of LH in conjunction with FSH is utilized for clarifying the causes of amenorrhea in women and clarifying the causes of testicular failure in men. The surge of LH has a compact relation with the ovulation in menstrual cycle. The Ovulation is always occurred in 24-36 hours after the surge of LH. SO the determination and monitoring of the concentration of serum LH in menstrual cycle can define the optimal period of fertility. Series detections of LH for 6-8 days in mid-cycle of women with regular menstrual cycles can make out the release surge. Determination of LH is useful in the diagnosis and treatment of infertility and pituitary and gonadal disorders.