Pre-test preparation or requirements
• Sample can be drawn at any time. No fasting or special preparation required.
• Sample should taken in plain vial.
Significance of test
Total protein measures all proteins in serum including albumin and globulin. Albumin being the major part.
The only clinical situation that causes an increase in serum albumin is acute dehydration.
A decreased albumin level, either from depressed synthesis or increased losses.
A decrease in albumin synthesis is caused by:
End-stage liver disease
Intestinal malabsorption syndromes
Albumin losses in:
Severe burns because the skin is the most important extra storage pool for albumin.